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Bruno Bastos Application PackageBastos Bruno Last Name First Name Middle Initial 1501 W 21St St Miami Beach Home Address City FL 33140 State Zip Code 78645328847865962000 HomeWork Brunobmd@icloud.com Email Address 6173206498 Cellular Business Address City State Zip Code Occupation:Business Name: Please list your preferences in order of ranking [1] first choice [2] second choice, and [3] third choice. Please note that only three (3) choices will be observed by the City Clerk’s Office. (Regular Boards of City) Choice 1: Choice 2: Choice 3: Health Advisory Committee Health Facilities Authority Board Parks and Recreational Facilities Board BOARD AND COMMITTEE APPLICATION FORM Note:If applying for the At-Large position of the Historic Preservation Board, please answer the below questions: Have you ever resided in one of the City's Historic Districts for at least one year?No No Address in City Historic District submitted. Professional License License Number Issuance Date Expire Date Florida Department of Health Licensed Health Care ME105209 7/27/2009 1/31/2025 Note:If you are seeking appointment to a professional seat (e.g. attorney, architect, etc.), you must attach a copy of your currently effective corresponding professional license. Pursuant to City Code section 2-22(4) a, b and c: Members of Agencies, Boards, and Committees shall be affiliated with the city. This requirement shall be fulfilled in the following ways: YesResident of the City for a minimum of six (6) months: Demonstrate an ownership interest in a business established in the City for a minimum of six (6) months:No AFFILIATION WITH THE CITY OF MIAMI BEACH a. ● I am resident of:South Beach Or b. "Ownership Interest" shall mean the ownership of ten percent (10%) or more (including the ownership of 10% or more of the outstanding capital stock) in a business. "Business" shall mean any sole proprietorship, sponsorship, corporation, limited liability company, or other entity or business association. c.Full-time employee of such a business (for a minimum of six months); and I am based in an office or other location of the business that is physically located in Miami Beach (for a minimum of six months):No Notwithstanding the requirements set forth herein, the qualified full-time employee of a business must be approved by a 4/7th vote of the Mayor and City Commission. NOTE: Members of Agencies, Boards, and Committees shall be required to demonstrate compliance with the City affiliation requirements of section 2-22 (4) a and b of the Miami Beach City Code by executing an affidavit, stipulating that they have met either (or both) of said affiliation requirements. The original affidavit shall be filled with the Office of the City Clerk prior to being sworn in as a member. Or No● Have you ever been convicted of a felony:If yes, please explain in detail: ● Do you currently have a violation(s) of City of Miami Beach codes:No If yes, please explain in detail: ● Do you currently owe the City of Miami Beach any money:No If yes, please explain in detail: ● Are you currently serving on any City Boards or Committees:No If yes, which board? ● Are you presently a registered lobbyist with the City of Miami Beach?No ● I am applying for an appointment because I have special abilities, knowledge and experience. Please list below: NOTE: IF APPOINTED, YOU WILL BE REQUIRED TO FOLLOW CERTAIN LAWS THAT APPLY TO CITY BOARD/COMMITTEE MEMBERS. THESE LAWS INCLUDE, BUT ARE NOT LIMITED TO: o Prohibition from directly or indirectly lobbying city personnel (Miami Beach City Code section 2-459). o Prohibition from contracting with the city (Miami-Dade County Code section 2-11.1). o Prohibition from lobbying before board/committee you have served on for period of one year after leaving office (Miami Beach Code section 2-26) o Requirement to disclose certain financial interests and gifts (Miami-Dade County Code section 2-11.1). o Sunshine Law - Florida's Government-in-the-Sunshine Law was enacted in 1967. Today, the Sunshine Law regarding open government can be found in Chapter 286 of the Florida Statutes. These statutes establish a basic right of access to most meetings of Boards, Commissions, and other governing bodies of state and local governmental agencies or authorities. o Voting conflict - Form 8B is for use by any person serving at the county, city, or other local level of government on an appointed or elected Board, Council, Commission, Authority, or Committee. It applies equality to members of advisory and non-advisory bodies who are presented with a voting conflict of interest under Section 112.3143. Florida Statutes. ● In what organization(s) in the City of Miami Beach do you currently hold membership in? No Organization Information Submitted. ● List the address of all properties owned or in which you have an interest within the City of Miami Beach: No Owned Property Information submitted. If so, which department and title?No● Are you now employed by the City of Miami Beach: ● Pursuant to City Code Section 2-25 (b): Do you have a parent, spouse, child, brother, or sister who is employed by the City of Miami Beach?No If "Yes", identify person(s) and department(s): No relative's information submitted. BOARD & COMMITTEE FINANCIAL ACKNOWLEDGEMENT STATEMENT Acknowledgement of fines/suspension for Board/Committee Members for failure to comply with Miami-Dade County Financial Disclosure Code Section 2-11.1(i)(2) I understand that no later than July 1, of each year all members of Boards and Committees of the City of Miami Beach, including those of a purely advisory nature, are required to comply with Miami-Dade County Financial Disclosure Requirements. One of the following forms must be filled with the City Clerk of Miami Beach, 1700 Convention Center Drive, Miami Beach, Florida, no later than 12:00 noon of July 1, of each year: 1. A "Source of Income Statement;" or 2. A "Statement of Financial Interests (Form 1)¹ ;" or 3. A Copy of your latest Federal Income Tax Return. Failure to file one of these forms, pursuant to the Miami-Dade County Code, may subject the person to a fine of no more than $500, 60 days in jail, or both. _____________________________ ¹ Members of the Planning Board and Board of Adjustment will be notified directly by the State of Florida, pursuant to F.S. §112.3145(1)(a), to file a Statement of Financial Interests (Form 1) with the Miami-Dade County Supervisor of Elections by 12:00 noon, July 1. Planning Board and Board of Adjustment members who file their Form 1 with the County Supervisor of Elections automatically satisfy the County’s financial disclosure requirement as a Miami Beach City Board/Committee member and need not file an additional form with the Office of the City Clerk. However, compliance with the County disclosure requirement does not satisfy the State requirement. DIVERSITY STATISTICS REPORT The following information is voluntary and has no bearing on your consideration for appointment. It is being asked to comply with City diversity reporting requirements. WhiteRace/Ethnic Categories What is your race? No details providedOther Description: Gender:Male Are you Spanish/Hispanic/ Latino? Mark the "No" box if not Spanish / Hispanic / Latino.Yes Physically Challenged:No UNDER PENALTIES OF PERJURY, I DECLARE THAT I HAVE READ THE FOREGOING APPLICATION AND THAT THE FACTS STATED IN IT ARE TRUE. ADDITIONALLY, I AGREE AND ACKNOWLEDGE THAT ANY FALSE STATEMENTS OR FALSE INFORMATION SUBMITTED AS PART OF THIS APPLICATION SHALL BE A BASIS FOR MY REMOVAL FROM A CITY BOARD OR COMMITTEE. I HAVE RECEIVED, READ, AND WILL ABIDE BY CHAPTER 2, ARTICLE VII, OF THE MIAMI BEACH CITY CODE, ENTITLED “STANDARDS OF CONDUCT FOR CITY OFFICERS, EMPLOYEES AND AGENCY MEMBERS” AND ALL OTHER APPLICABLE CITY, COUNTY, AND/OR STATE LAWS AND STATUTES ACCORDINGLY. I Bruno Bastos agreed to the following terms on 2/8/2023 4:13:09 PM Received in the City Clerk's Office by: Name of Deputy Clerk Control No. Date Board and Committee Application Checklist: Please ensure you have provided all information before applying or reapplying to any Board and Committee. YES YES YES YES I have answered all questions fully. I have uploaded a current resume, photograph, and a copy of any applicable professional license. I have completed and attached the Board & Committee Financial Acknowledgment Statement. I have completed and attached the Diversity Statistics Report. If you have any questions, please contact the Office of the City Clerk via email: BC@miamibeachfl.gov or telephone: 305.673.7411 Note: Florida Statutes 119.071: The role of the Office of the City Clerk is to receive and maintain forms filed as public records. If your home address, telephone numbers, and/or photograph are exempt from disclosure and you do not wish your home address, telephone numbers, and/or photograph to be made public, please: 1) Use your office or other address for your mailing address; 2) Use your office or other telephone number for your contact number; and 3) Do not attach a photograph. CURRICULUM VITAE General Information Name: Bruno Rossi Bastos Home Address: 1501 W 21st Street, Miami Beach FL 33140 Office Address: Miami Cancer Institute, 8900 N Kendall Dr, Suite 2N429, Miami, FL 33176 Work Phone: (786) 596-2000 Cell Phone: 617.320.6498 E-mail: brunoba@baptisthealth.net Place of Birth: Brazil Citizenship: US, Brazil, Italy Languages: English, Spanish, Portuguese (Native) Medical Degree Education: 03/1995-12/2001: M.D., Universidade Federal da Bahia ECFMG Certification: May 1, 2002 Certificate number 0-639-284-1 Postdoctoral Training: 07/2008-09/2009: Special Clinical Fellow, Developmental Therapeutics Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School. Boston, MA 07/2005-06/2008: Clinical Fellow, Hematology/Oncology Department of Medicine (Hematology/Oncology dept), University of Miami. Miami, FL 06/2002-06/2005: Resident Internal Medicine Department of Medicine, University of Miami, Miami, FL 01/2002-06/2002: Application process for US residency. State of Florida Appointment: 2015-19: Appointed by Governor of Florida to the Florida Center for Brain Tumor Research Scientific Advisory Council Clinical Appointments May 2019-Present: Hematologist/Oncologist (Focus in Genito-urinary Malignancies/Phase 1 Clinial Trials.) Miami Cancer Institute/Baptist Health Medical Group Oncology, Baptist Medical Hospital, South Miami Hospital, West Kendall Baptist Hospital, Homestead Baptist Hospital, Mariners Hospital. October 2009- May 2019: Hematologist- Oncologist. Staff Department of Hematology/Oncology, Cleveland Clinic FL. Weston, FL. December 2008- October 2009: Physician/Moonlighter Internal Medicine. Brigham and Women’s Hospital. Boston, MA. Academic Appointments: 2015-19: Clinical Assistant Professor of Medicine. Case Western Reserve University – School of Medicine 2013-19: Program Director of the Cancer Research Fellowship Program at Cleveland Clinic Florida 2010-: Clinical Assistant Professor, Department of Medicine, Florida International University, Herbert Wertheim College of Medicine 2010-: Affiliate Assistant Professor, Charles E. Schmidt College of Medicine, Florida Atlantic University Hospital or Affiliated Institution Leadership Appointments: 2022: Member. Physician Grateful Advisory Council. Baptist Health Foundation 2022: Ambassador. Baptist Health Foundation. 2022: Group Leader. John Hopkins University School of Medicine. Gather-ed platform/Medical Logix. 2022: Advisor. Sanofi GU Oncology. Board of Advisors. 2020: Committee Member. Research Steering Committee. Miami Cancer Institute 2019: Committee Member. CSRC. Miami Cancer Institute 2019: Lead Physician, Multiple Tumors/Phase I clinic. Miami Cancer Institute 2019: Site Research Leader, US ONCOLOGY at MCI 2019: Committee Member, ECOG-ACRIN GU Early Modality Committee. 2019: Member. MSK-EDD Alliance Early Phase Clinical Trials. 2018-19: Committee Member Physician Engagement. CCF 2017: Mentor ASCO Diversity Mentorship Program 2017: Committee Member FLASCO Cancer Disparities 2017: Volunteer ASCO Volunteer Corps 2016: Committee Member Education Committee- International Association for the Study of Lung Cancer IASLC 2016: Committee Member Communications Committee - International Association for the Study of Lung Cancer IASLC 2015-19: Committee Member of the Global Patient Services (GPS) Advisory Council, Cleveland Clinic Florida 2013: Committee Member, Prostate Cancer Advisory Board, FPCR 2012: Committee Member, Developmental Therapeutics, the Alliance for Clinical Trials in Oncology 2011-19: Medical Director of Cancer Research, Department of Hematology Oncology, Cleveland Clinic Florida 2011-19: Program Director, Visiting Researcher Fellowship in Oncology 2011-19: Responsible Investigator, Cleveland Clinic Florida, NIH-sponsored Community Clinical Oncology Program (CCOP) Clinical Trials 2010-19: Co-Director of the Lung Cancer Center, Cleveland Clinic Florida 2010: Director of the Oncology Tumor Board, Cleveland Clinic Florida 2010-19: Committee Member of the Pharmacy & Therapeutics Committee, Cleveland Clinic Florida 2009: Editorial Board Team of the Journal of Thoracic Disease Professional Societies (Membership): 2020: European Society of Medical Oncology (ESMO) 2018: Society for Neuro-Oncology (SNO) 2018: ACCRU, Academic and Community Cancer Research United 2014: SWOG 2014: Florida Society of Clinical Oncology (FLASCO) 2011: Cancer Trials Support Unit (CTSU) 2010: International Association for the Study of Lung Cancer (IASLC) 2010: Alliance 2010: ECOG-ACRIN 2009: CTEP/NIH 2008: Massachusetts Medical Society 2009: American Association for Cancer Research (AACR) 2006: American Society of Clinical Oncology (ASCO) 2006: American Society of Hematology (ASH) 2003: American College of Physicians (ACP) 2002: American Medical Association (AMA) Awards and Honors: 2022: Author!Author!Day. National Library Week. Miami Cancer Institute. Honored Staff Author 2021: Author!Author!Day. National Library Week. Miami Cancer Institute. Honored Staff Author 2018: Award of Excellence in Research & Academic Achievement. Maroone Cancer Center 2017 2016: First Prize. Poster Competition at the Florida Bladder Cancer Symposium 2016: Appreciation Award, Caregiver Celebration-Cleveland Clinic. Core Value: Compassion 2013: Caregiver Hero-Cleveland Clinic Florida 2009: ASCO/AACR Workshop Methods in Clinical Cancer Research Scholarship 2006: AMGEN Young Investigator Forum Award 2006: National Lung Cancer Partnership Travel Award 2003: Internal Medicine Residency Annual Case Presentation Competition, University of Miami 2003: Student Inpatient Teaching Award, School of Medicine, University of Miami 2000: CICAN- State of Bahia Cancer Center Scholarship 2000: PIBIC/CNPq-Brazilian Scholarship for Graduate Research Special Externship: 2005: NIH/NCI - Clinical Rotation in Hematology Ad Hoc Reviewer: 2021: FLASCO - Oncology Fellow & Resident Educational Training Program. Abstract Reviewer. March 19, 2022. 2018: JCO Precision Oncology 2017: Journal of Community and Supportive Oncology 2017: HPB 2016: JAMA Oncology 2016: Frontiers in Oncology 2016: Journals of the American College of Clinical Pharmacy 2013: Drug Design, Development and Therapy 2013: Lung Cancer: Targets and Therapy 2013: Onco-Targets and Therapy 2013: Pharmacogenomics and Personalized Medicine. 2013: Frontiers in Thoracic Oncology 2013: American Journal of Clinical Oncology 2013: Oral Oncology 2012: Pharmacotherapy Poster Judge Competition: 2014-2016: Cleveland Clinic Florida - Resident and Fellow Research Week. Poster Judge. Weston- FL 2013: Florida Chapter Meeting/American College of Physicians. Poster Judge TEACHING a. International Presentations: 2021: Update in targeted therapies in lung cancer (RET, ROS1, NTRK and KRAS G12C). Brasilia, Brazil. December 2021. Invited Speaker 2021: Update in targeted therapies in lung cancer (RET, ROS1, NTRK and KRAS G12C). VIII Simposio Internacional de Cancer de Pulmao. Sao Paulo. March 6th, 2021. Invited Speaker. 2020: Targeted therapies and Immunotherapy in Lung Cancer: COVID-19 impact. Online live round-table conference. April 29, 2020. Sao Paulo, Brazil www.pcomunic.com.br/onconnection. Invited Speaker 2019: Immunotherapy in mutation driven tumors: when to offer? VII Simposio Internacional de Cancer de Pulmao. March 15-2019. Sao Paulo, Brazil. Invited Speaker 2019: Update 2019 in the management of targeted therapies (BRAF, MET, RET, ROS1, HER2). VII Simposio Internacional de Cancer de Pulmao. March 15-15, 2019. Sao Paulo. Brazil. Invited Speaker. 2019: Immunotherapy versus Cytotoxic in the Therapy of Cancer. Medical Association of the Bahamas scientific Conference. March 13-15, 2019. Nassau, Bahamas. Invited Speaker. 2017: Novel immunotherapeutic combinations in Lung Cancer. 55th Annual Meeting of JSCO. October 20-22, 2017. Yokohama, Japan. Invited speaker 2017: Update in Head and Neck Cancer. Best of ASCO 2017 Panama. Panama City, Panama. Invited Speaker. 2016: Update in Head and Neck and CNS malignancies. Best of ASCO 2016. Panama City, Panama. Invited Speaker 2014: Moving to Personalized Medicine in Lung Cancer Diagnosis and Therapy. IASLC/ESMO Session Chair. LALCA 2014. Lima, Peru. Invited Moderator 2014: Therapy of EGFR/ALK Resistant Lung Cancer. LALCA 2014, Lima, Peru. Secretary. Round Table #10. Invited Moderator b. Invited National/Regional Presentations: 2022: Improving the Care of Patients with Advanced and Metastatic Renal Cell Carcinoma through a Digital Inter-professional Social Learning Platform. Johns Hopkins University School of Medicine. CME/CE event. Gather-ed platform/Medical Logic. Group Leader. 2022: Best of ESMO 2022. Treatment of Oligo-metastatic Prostate Cancer. Fort Lauderdale. Speaker 2022: Targeted Oncology. Virtual Case-based Roundtable Meeting on Prostate Cancer. Moderator. August 31, 2022. Co-moderator 2022: ASCO Direct. Prostate Cancer. Best of ASCO Review, Philadelphia, FL Speaker 2022: ASCO Direct. Prostate Cancer. Best of ASCO Review. Jacksonville, FL Speaker 2022: OncLive State of the Science Summit. Genitourinary Cancer. Miami-FL. May 18th 2022. Program Chair/Ambassador. 2022: OncLive State of the Science Summit. Frontline Treatment of mRCC (CABOSUN, CheckMate 9ER, CheckMate 214, CLEAR) Speaker. Genitourinary Cancer. Miami-FL. May 18th 2022. Speaker 2022: OncLive State of the Science Summit. Second and Later Line Treatment of mRCC/TIVO-3) Speaker. Genitourinary Cancer. Miami-FL. May 18th 2022. Speaker 2022: MCI-Grand Rounds. Targeting Cancer Cell Metabolism. May 9th, 2022. Speaker 2021: MSK Experimental Drug Development (EDD) Phase I Meeting. Virtual. Speaker. 2021: Prostate Cancer: Sequencing for Metastatic Castration Resistant. Targeted Therapies. Case-Based Round Table Meeting. Webinar. August 18th, 2021. Co-moderator 2021: Oncology I. Cleveland Clinic Florida Internal Medicine Board Review. Speaker. July 2021 2021: Grand Rounds Family Medicine Residency. Oncology - Board Review. Borinquen Residency Program. May 2021. Spaker 2020: Oncology I. Cleveland Clinic Florida Internal Medicine Board Review. Speaker. July 2020 2020: ASCO virtual Direct Highlights. Genitourinary Cancer – Prostate Cancer. Jacksonville FL. Total Health Conferencing. July 2020. Speaker. 2019: ESMO 2019 – GU Oncology Highlights. Total Health Conference. November 16, 2019. Fort Lauderdale, Florida. Speaker 2019: Oncology I. Cleveland Clinic Florida Internal Medicine Board Review. Speaker 2019: Targeted Therapies and Side Effects. 9th Annual Winter Oncology Symposium. March 1-2, 2019. Fort Lauderdale. Speaker 2019: Emerging Role of Immunotherapy in Head and Neck Cancer. 2019 Multidisciplinary Head and Neck Cancer. Fort Lauderdale FL. Speaker 2018: Oncology I. Cleveland Clinic Florida Internal Medicine Board Review. Speaker 2018: Emerging Role of Immunotherapy in Head and Neck Cancer. 2018 Multidisciplinary Head and Neck Cancer. Key Largo FL. Speaker 2018: Round table. Case discussion Skin and Thyroid Cancer cases . Multidisciplinary Head and Neck Cancer. Key Largo FL. Panelist 2018: Round table. Case discussion Head & Neck Cancer-Immunotherapy. Multidisciplinary Head and Neck Cancer. Key Largo FL. Panelist 2018: Targeted Therapies for Metastatic Disease. Tampa Florida. Bladder Cancer Update. CME-event. Speaker 2018: Brain Tumor Summit. University of Florida. Tallahassee FL. Scientific Advisor Board Member. 2018: First GU Oncology Symposium. Cleveland Clinic Florida January 2018. Challenge the Professor GU Oncology clinical cases. January 2018. Weston-FL. Speaker and meeting organizer 2017: Consequences of the Increasing Use of Immunomodulators to Treat Patients with Cancer. Medical Grand Rounds. Cleveland Clinic Florida. August 23rd, 2017. Speaker 2017: Update in Bladder Cancer. Target Therapies for Metastatic Disease. Hard Rock Café, Fort Lauderdale, FL. August 22, 2017. Speaker 2016: Update in Lung Cancer. Medical Grand Rounds. Larkin Internal Medicine Program. Miami-FL. Speaker 2016: Using Precision Medicine in the neo-Adjuvant Treatment for the treatment of Muscle-Invasive Bladder Cancer (MIBC). Florida Bladder Cancer Symposium. November 2016. Speaker 2016: Immunotherapy in Head and Neck Cancer. 2016 Multidisciplinary Head and Neck Cancer. Fort Lauderdale-FL. Speaker 2014: Clinical Trials and Novel Agents in Advanced Prostate Cancer. Potential for Inter-Institutional Collaboration. Third Annual Florida Prostate Cancer Research Symposium. Session Moderator 2013: Clinical Trials and Novel Agents in Advanced Prostate Cancer. P otential for Inter-Institutional Collaboration. Second Annual Florida Prostate Cancer Research Symposium. Speaker 2013: Chemotherapy in Low Grade Gliomas; First Annual International Brain Tumor & Spine Surgery Symposium, Jagelman Conference Center, Cleveland Clinic, Weston FL. Speaker 2012: Chemotherapy in metastatic brain tumors; First Annual International Brain Tumor & Spine Surgery Symposium, Jagelman Conference Center, Cleveland Clinic, Weston FL. Speaker 2012: Chemotherapy in Low Grade Gliomas; First Annual International Brain Tumor & Spine Surgery Symposium, Jagelman Conference Center, Cleveland Clinic, Weston FL. Speaker. 2011: Treatment of Medulloblastoma with Hedgehog Pathway Inhibitors; 2011 Florida Brain Tumor Biomedical Technology Summit on May 14, 2011 at the Peabody Hotel in Orlando, FL. Speaker. 2008: Consolidation Docetaxel After Concurrent Chemoradiotherapy with Carboplatin and Irinotecan in Unresectable Stage III NSCLC,; Boston Medical Center, Boston, MA. Speaker. 2006: Overcoming Cisplatin Resistance with mTOR Inhibition; 10th Annual Joint Cancer Conference of the Florida Universities, Orlando FL. Speaker. 2004: Complete Remission of Oral Plasmablastic Lymphoma with Antiviral Therapy; 8th Annual Joint Cancer Conference of the Florida Universities, Orlando FL. Speaker. 2003: A Man Presenting with Tooth Pain; Clinical Case Presentation, American College of Physicians, St. Petersburg, FL. Speaker. c. Community Outreach/Philanthropic Activities 2022: Invited Speaker, Fund Raiser and Organizer. Swim Across America – Open Swim Fund raising Event. Islamorada, FL 2021: Invited Guest. Heat-Help-/cure 2022 Launch Event. Miami-FL 2017: Speaker. Bonnie Adadrio Round Table Series in Lung Cancer. 2011: Moderator. Cleveland Clinic Online Health Chats. Lung Cancer. 2010: Moderator. Man to Man Group – Monthly Prostate Cancer Support Group Meeting. d. Mentorship: 2017: Mentorship-ASCO Diversity Mentoring 2016: Mentorship–ASCO/JSCO 2011-2016: Mentorship. The Weber Family Summer Scholar Program. d. Clinical Teaching 2018- Monthly Research Oversight Meeting. MCI.Organizer/Presenter 2018- Bi-weekly MCI Tumor Board (GU) Speaker 2008- Bi-weekly Cleveland Clinic Tumor Board (GU/Neuro Oncology/Thoracic Oncology/Head & Neck). Speaker 2008- Internal Medicine Residency Program – Cleveland Clinic Florida. Faculty/Attending. 2008- Geriatrics Fellowship Program – Cleveland Clinic Florida. Faculty/Attending. e. Media Publications 2022: Youtube. https://youtu.be/EO2ekPZHUFI CLINICAL RESEARCH: ACTIVE GRANTS Industry: ACTIVE TRIALS: USOR 20186 Ph2 Tumor-Agnostic Precision TAPISTRY. Role at MCI. PI. USOR 19151 Ph1/2 MRTX849 Solids KRAS G12C. Role at MCI. PI USOR 19144 Biomarker Study to Determine Frequency of DNA-repair Defects in Men with Metastatic Prostate Cancer. Sponsor: Jansen Research & Development, LLC. Role at MCI: PI USOR 18057. Phase 1/2, open-label, first-in-human study of BMS-986249, an anti-T lymphocyte-associated protein 4 (CTLA-4) ProbodyTM monoclonal antibody (mAb) of ipilimumab, alone and in combination with nivolumab (anti-programmed cell death 1 [PD-1]), in participants with advanced solid tumors. Funding Agency: US Oncology. Role: PI at MCI. Federal: A31102. Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors. Role at MCI. PI PIPELINE: Concept Development/IIT: 2018-BAS-001 Phase I/II Study of the indenoisoquinoline TOP1 inhibitor LMP400 (indotecan) with olaparib in patients with homologous recombination deficient advanced solid tumors. 2021-BAS-001 Phase 1 Study of Rosiglitazone and Carboplatin in Patients with Advanced Solid Tumors. 2022-BAS-001 Phase 1 study of Tivozanib with Belzutifan in patients with advanced Renal Cell Carcinoma. 2022-RETRO-BAS-001: Minorities Participation in Phase I Clinical Trials, a community center experience. 2022-RETRO-BAS-002: Clinical Outcomes of Treatment Sequencing in AR-V7 Negative Metastatic Castration-Resistant Prostate Cancer (mCRPC) Patients PREVIOUS GRANTS Federal: 184-313 RTOG 0924 Androgen deprivation therapy and high dose radiotherapy with or without whole-pelvic radiotherapy in unfavorable intermediate or favorable high-risk prostate cancer: a phase III randomized trial. Funding Agency: NCI Role: PI at CCF site A151216 Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial (ALCHEMIST). Funding Agency: NCI Role: PI at CCF site A081105 Randomized double blind placebo controlled study of erlotinib or placebo in patients with completely resected epidermal growth factor receptor (EGFR) mutant non- small cell lung cancer (NSCLC). Funding Agency: NCI Role: PI at CCF site EA5142 A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers. Funding Agency: NCI Role: PI at CCF site DFCI1Y17 “NCT02888743 / 10021” - Durvalumab and Tremelilumab with or without High or Low-Dose Radiation Therapy in Treating Patients with Metastatic Colorectal or Non-Small Cell Lung Cancer. Funding Agency: NCI Role: PI at CCF site S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients with Bladder Cancer. Funding Agency: NCI Role: PI at CCF site ECOG 1505, a phase III randomized trial of adjuvant chemotherapy with or without bevacizumab for patients with completely resected stages IB (≥4 cm) - IIIA Non-Small Cell Lung Cancer (NSCLC). Funding Agency: NCI Role: PI at CCF site. CTSU E 5508, a randomized phase III study of maintenance therapy with bevacizumab, pemetrexed, or a combination of bevacizumab and pemetrexed following carboplatin, paclitaxel and bevacizumab for advanced non-squamous NSCLC. Funding Agency: NCI. Role: PI at CCF site. ECOG 1305, a phase III randomized trial of chemotherapy with or without bevacizumab in patients with recurrent or metastatic head and neck cancer. Funding Agency: NCI. Role: PI at CCF site. CALGB 90601, a randomized double-blinded phase III study comparing gemcitabine, cisplatin and bevacizumab to gemcitabine, cisplatin and placebo in patients with advanced transitional cell carcinoma. Funding Agency: NCI. Role: PI at CCF site. CALGB 90802, a randomized phase III trial comparing everolimus versus everolimus plus bevacizumab for advanced renal cell carcinoma progressing after treatment with tyrosine kinase inhibitors. Funding Agency: NCI. Role: PI at CCF site. SWOG S0931, EVEREST: EVErolimus for renal cell carcinoma ensuing surgical therapy, a phase III study. Funding Agency: NCI. Role: PI at CCF site. SWOG 1404 a Phase III randomized trial comparing Physician/Patient of Choice of Either High Dose Interferon or Ipililumab to MK-3475 (Pembrolizumab) in patients with high risk resected melanoma. Industry: XL184-313 A Randomized, Double-Blind, Controlled Phase 3 Study of Cabozantinib in Combination with Nivolumab and Ipilimumab versus Nivolumab and Ipilimumab in Subjects with Previously Untreated Advanced or Metastatic Renal Cell Carcinoma of Intermediate or Poor Risk. Sponsor: Exelixis. Role at MCI: Co-PI PCR3011 A Randomized, Double-blind, Placebo-controlled Phase 3 Study of Apalutamide in Subjects with High-risk, Localized or Locally Advanced Prostate Cancer Who Are Candidates for Radical Prostatectomy. Sponsor: Janssen Research & Development, LLC. Role at MCI: Co-PI Actuate 1801 Phase 1/2 Study of 9-ING-41, a Glycogen Synthase Kinase-3 Beta (GSK- 3β) Inhibitor, as a Single Agent and Combined with Chemotherapy, in Patients with Refractory Hematologic Malignancies or Solid Tumors. Funding Agency: Actuate. Role: PI at MCI. TP-0903-101 A Phase 1a / 1b, First-in-human, Open-label, Dose-escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-0903 Administered Daily for 21 Days to Patients with Advanced Solid Tumors. Funding Agency: Tolero. Role: PI at MCI USOR18235 A Phase 1 Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants with Advanced Malignancies (AB928CSP0005). Sponsor: Arcus Biosciences, Inc. Role at MCI: PI. USOR 18214 A Phase 1/2 Study of Galinpepimut-S in Combination with Pembrolizumab (Mk-3475) in Patients with Selected Advanced Cancers. Sponsor: Sellas Life Sciences Group. Role at MCI. PI. TPST1120-001 A Phase 1/1b Open-label, Dose-escalation and Dose-expansion Study of TPST-1120 as a Single Agent or in Combination With Systemic Anti-Cancer Therapies in Subjects With Advanced Solid Tumors. Sponsor: Tempest Therapeutics. Role at MCI. PI. QUILT-3.055 A Phase 2b, Single-Arm, Multicohort, Open-Label Study of ALT-803 in Combination with a PD-1/PD-L1 Checkpoint Inhibitor in Patients Who Have Disease Progression Following an Initial Response to Treatment with PD-1/PD-L1 Checkpoint Inhibitor Therapy. Sponsor Altor Bioscience. Role at MCI: PI. CheckMate 568 Nivolumab in Combination with Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination with Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer. Sponsor: Bristol Meyers Squibb Role at CCF: PI Amount: $183,825.00 STARTRK-2: An open label, multicenter, global phase 2 basket study of entrectinib for the treatment of patients with locally advanced or metastatic solid tumors that harbor NTRK1/2/3, ROS1, or AL gene rearrangement. Sponsor: Ignyta. Role at CCF: Co-PI I4E-MC-JXBD, a randomized, double-blind, phase 2 safety study of cetuximab, using ImClone versus Boehringer Ingelheim, in combination with chemotherapy as first-line in patients with recurrent or metastatic head and neck cancer. Sponsor: Lilly Role at CCF: PI Amount: $107,015.00 ARQ197-218, a phase II randomized open-label study of erlotinib plus tivantinib (ARQ 197) versus single agent chemotherapy in previously treated KRAS mutation positive subjects with locally advanced or metastatic NSCLC. Funding Agency: Arqule. Role: PI at CCF site. GO27820, a randomized phase II, multicenter, double-blind, placebo-controlled study evaluating the efficacy and safety of onartuzumab (MetMAb) in combination with paclitaxel + cisplatin or carboplatin as first-line treatment for patients with stage IIIB (T4 disease) or IV squamous NSCLC. Sponsor: F. Hoffman-La Roche Ltd. Role: PI at CCF site. Amount: $206,707.50 A randomized double-blind, phase 2 study of Erlotinib in combination with OSI-906 or Placebo in chemo naïve patients with advanced NSCLC with activating mutations of the Epidermal Growth Factor Receptor (EGFR) gene. Sponsor: Astellas. Role: PI at CCF site. Amount: $ 118,229.60 A phase II randomized double-blind, placebo controlled, multicenter study of VS-6063 in subjects with malignant pleural mesothelioma. Sponsor: Verastem, Inc. Role: PI at CCF site. Amount: $92,373.56 An open-label, multi-center, Expanded Treatment Protocol of oral LDK378 in adult patients with non-small cell lung cancer (NSCLC) characterized by ALK positivity. Sponsor: Novartis. Role: PI at CCF site. Amount: $132,188.00 A multicenter, open-label phase 2 study of the safety and activity of levantinib (E7080) in subjects with KIF5B-RET-Posiitive Adenocarcinoma of the Lung. Sponsor: Eisai Role: PI at CCF site TIGER-2: A Phase 2, Open-label, multicenter, safety and efficacy study of oral CO-1686 as 2nd Line EGFR-directed TKI in Patients with Mutant EGFR NSCLC. Sponsor: Clovis Oncology. Role: PI at CCF site. Amount: $ 112,120.00 HALO1Y15 A Phase 1b Open-Label Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) Combined with Pembrolizumab in Subjects with Selected Hyaluronan-High Solid Tumors. Funding Agency: Halozyme Therapeutics. Role: Co-PI at CCF site IIT: CASE 1516 - A Phase II Trial of Pembrolizumab Sequentially Following Single Fraction Non-Ablative Radiation to One of the Target Lesions, in Previously Treated Patients with Stage IV NSCLC. Funding Agency: Cleveland Clinic Role: Co-PI at CCF BIBLIOGRAPHY A. Abstracts 1. Brenner N, Bastos B. Perioperative DD-MVAC- a Safe and Efficacious Treatment for MIBC; Results of a Retrospective Community Center Study with Clinical Correlated of Toxicity and Response. ASCO 2015. J Clin Oncol 33, 2015 (suppl; abstr e15540) 2. Brenner N, Bastos B. Radiographic patterns of progression in patients with EGFR mutant NSCLC undergoing EGFR TKI therapy. ASCO 2015. J Clin Oncol 33, 2015 (suppl; abstr e19108) 3. Manthri S, Bastos, B. A community hospital experience in the use of peri- operative dose-dense MVAC in patients with muscle-invasive bladder cancer (MIBC) treated with either robotic cystectomy (RC) or open cystectomy (OC). ASCO 2014 4. Manthri S, Bastos, B. A community hospital experience on the outcome of patients with different genetic variant epidermal growth factor receptor (EGFR) mutant non-small cell lung cancer (NSCLC). ASCO 2014. 5. Bastos B, Diamond J, Hansen R, Gustafson D, Arnott J, Bray M, Sidor C, Messersmith W, Shapiro G. An open-label, dose escalation, safety, and pharmacokinetic study of dc administered orally to patients with advanced cancer. J Clin Oncol 27:15s, 2009 (suppl; abstr 3520) 6. Bastos B, Roman E, Negret L, Takita C, Lobo C, Lopes G, Farfan N, Karr M, Rocha-Lima C, Raez LE. Consolidation Docetaxel After Concurrent Chemoradiotherapy with Carboplatin and Irinotecan in Unresectable Stage III NSCLC. J of Thor Onc Oct 2006, Vol 1(8), 902a. 7. Bastos B, Wangpaijit M, Wu C, Robles C, Savaraj N. Overcoming Cisplatin and VP- 16 Resistance with mTOR Inhibition in Small Cell Carcinoma Patients. J of Thor Onc Oct 2006, Vol 1(8), 905a. 8. Lopes G, Bastos B, Ahn E, Quesada J, Allison M, Flores A, Ribeiro A, Levi J, Macintyre J, Rocha-Lima CM. A Phase II Trial of Capecitabine and Docetaxel in Patients with Previously Treated Pancreatic Cancer. J Clin Oncol ASCO Annual Meeting Proceedings Part I. Vol 24, No. 18S (June 20 Supplement), 2006:14111. B. Educational Exhibits/Posters 1. Martin Gutierrez, Claire Friedman, Georgina V. Long, Paolo A. Ascierto, Ignacio Melero,Donald Richards, Bruno Bastos,Victor Moreno, Marc Uemura,Paul Conkling, Bradley R. Corr,Amy Kim, Li Zhu, Amy Hammell,Deepak Perumal, Armand Chouzy,Fernando Benavente, Ololade Awosemo, Dung LeAnti– Cytotoxic T Lymphocyte Antigen-4 (CTLA 4) Probody BMS-986249 ± Nivolumab (NIVO) in Patients (pts) With Advanced Cancers: Updated Phase 1 Results. ESMO 22. Poster 2. Mark Yarchoan, John Powderly, Bruno Bastos, Thomas Karasic, Oxana Crysler, Pamela Munster, Meredith McKean, Leisha Emens, Yvonne Saenger, Yasser Ged, Robert Stagg, Steve Smith, Anne Moon, Peppi Prasit, Thomas Dubensky, Sam Whiting, Susanna Ulahannan. A Phase 1 Study of TPST-1120 as a Single Agent and in Combination with Nivolumab in Subjects with Advanced Solid Tumors (NCT03829436). ASCO 22. Oral Presentation. 3. Thomas W. Flaig, Catherine Tangen, Siamak Daneshmand, Ajjai Shivaram Alva, M. Scott Lucia, David McConkey, Dan Theodorescu, Amir Goldkorn, Matthew I. Milowsky, Rick Bangs, Gary R. MacVicar, Bruno R. Bastos, Jared Fowles, Daniel Gustafson, Melissa Plets, Ian Murchie Thompson, Seth P. Lerner. SWOG S1314: A randomized phase II study of co-expression extrapolation (COXEN) with neoadjuvant chemotherapy for localized, muscle-invasive bladder cancer with overall survival follow up. ASCO GU 2022. J Clin Oncol 40, 2022 (suppl 6; abstr 536). 4. J. Sarantopoulos, A.A. Adjei, M. Beg, J. Melear, J. Thompson, F.Y. Tsai, J.C. Baranda, B. Bastos et al. A phase I, first-in-human, safety, pharmacokinetic, and pharmacodynamic study of oral dubermatinib (TP-0903) in patients with advanced solid tumours. ESMO Virtual Congress 2020. 18 Sep 2020. Session: Mini Oral – Developmental Therapeutics. Abstract 536MO. 5. Carneiro B, Cavalcante L, Bastos BR et al. Phase I study of 9-ing-41, a small molecule selective glycogen synthase kinase-3 beta (GSK-3β) inhibitor, as a single agent and combined with chemotherapy, in patients with refractory tumors. Developmental Therapeutics – Molecularly targeted Agents and Tumor Biology. Abstract 3506.ASCO20. 6. Gutierrez M, Long G, Friedman C, Richards D, Corr B, Bastos BR et al. Anti- CTLA-4 probody BMS-986249 alone or in combination with nivolumab in patients with advanced cancers: Initial phase I results. Developmental Therapeutics-Immunotherapy. Abstract 3058. ASCO2020. 7. Daniel Olson, Riyue Bao, Jacob B Alfred, Carrie Strand, Yuanyuan Zha, Timothy C. Carll, Brian Labadie, Bruno R. Bastos, Marcu O. Butler, Pamela N. Munster, Gary K. Schawrtz, Jason J. Luke. Correlateds of Overall Survival (OS) in metastatic uveal melanoma (mUM) and a randomized trial of cabozantinib (cabo) versus chemotherapy (chemo). Journal of Clinical Oncology 37, no. 15_suppl (May 20, 2019) 9506-9506. 8. Thomas W. Flaig, Catherine M. Tangen, Siamak Daneshmand, Ajjai Shivaram Alva, Seth P. Lerner, M. Scott Lucia, David James McConkey, Dan Theodorescu, Amir Goldkorn, Matthew I. Milowsky, Richard Carlton Bangs, Gary R. MacVicar, Bruno R. Bastos, Daniel Gustafson, Melissa Plets, Ian Murchie Thompson. SWOG S1314: A randomized phase II study of co-expression extrapolation (COXEN) with neoadjuvant chemotherapy for localized, muscle- invasive bladder cancer. J Clin Oncol 37, 2019 (suppl; abstr 4506) 9. Sadler D, Nahleh Z, Stone E, Samuel T, Bastos B et al. starting a cardio-oncology program: a simple approach for rapid growth. Global Cardio Oncology Summit. Tampa-FL. February 2019. 10. Sadler D, Nahleh Z, Stone E, Samuel T, Bastos B et al. Advancing the Starting and Sustaining a Cardio Oncology Program: Practical Model to Succeed Utilizing Existing Resources at Your Institution. Washington DC. January 2019. 11. Bastos B et al Neoadjuvant chemotherapy with Dose-Dense MVAC (Methotrexate, Vinblastine, Doxorubicin and Cisplatin) in patients with muscle- invasive bladder cancer in a community based hospital; a retrospective study. Florida Bladder Cancer Research Symposium. November 2016. FIRST PRIZE WINNER. 12. Bastos B Et al. Synergistic Combination of PD-1 and EGFR antibodies: a proposed phase I clinical trial utilizing nivolumab and cetuximab. 2016 Multidisciplinary Head and Neck Cancer Symposium. Scottsdale, Arizona. February 2016. 13. Marc A. Shapiro, James Stevenson, Emily Van Wagoner, Katherine Glass, Chad W Cummings, Nathan A. Pennell, Patrick C. Ma, Vamsidhar Velcheti, Bruno R. Bastos, Brian James Bolwell, Abdo Haddad. Impact of a Stage IV NSCLC care pathway on front-line (FL) and maintenance (M) chemotherapy use at the Cleveland Clinic Taussig. Poster Session. J Clin Oncol 33, 2015 (suppl; abstr 6609). 14. Eberechi Sandra Agwa, Francisco Almeida, Abdo Haddad, Bruno R. Bastos, Roy Lee, Xuefei Jia, Patrick Ma. Clinical implications of repeat tumor biopsy (RTB) in patients (pts) with advanced lung cancer (LC); the Cleveland Clinic (CC) experience. ASCO 2015. Poster Session. J Clin Oncol 33, 2015 (suppl; abstr 8077). 15. Jason John Luke, Jacob B Allred, Laura E. Horvath, Bruno R. Bastos, Charles Erlichman, Gary K. Schwartz. Randomized phase II study comparing the MET inhibitor cabozantinib to temozolomide (TMZ) or dacarbazine (DTIC) in ocular melanoma: A091201. ASCO 2015. Poster Session. J Clin Oncol 33, 2015 (suppl; abstr TPS9087). 16. Gerber D, Bastos B et. al. Randomized Phase 2 Study of Tivantinib (ARQ 197) Plus Erlotinib vs. Single-agent Chemotherapy in Previously Treated KRAS Mutant Advanced Non-Small Cell Lung Cancer (NSCLC). 2014 Chicago Multidisciplinary symposium in Thoracic Oncology November 2014 (Accepted for poster presentation). 17. Paul J. E. Miller, Mark S. Walker, Kurt W. Tauer, James Atkins, Kulumani M Sivarajan, Vipul M. Patel, Bruno R. Bastos, Krista Meyer, Joanna Roder, Lisa Uyeda, Suzanne Salazar, Corey J. Langer, Mark A. Socinski, David R. Spigel, Lee Steven Schwartzberg. Serum and tumor biomarkers predict outcome in the elung trial, a multicenter, randomized phase 2b study of standard platinum doublets (PD) plus cetuximab (CET) as first-line treatment of advanced non-small cell lung cancer (NSCLC). Selected as poster presentation for ASCO 2013. Chicago, IL. 18. L. S. Schwartzberg, K. Tauer, J. Atkins, K. Sivarajan, V. Patel, B. Bastos, C. Langer, M. A. Socinski, D. R. Spigel. LBA30 - eLung: A Multicenter, Randomized Phase IIb Trial of “Standard” Platinum Doublets plus Cetuximab (CET) as First-line Treatment of Recurrent or Advanced Non-Small Cell Lung Cancer (NSCLC). Proffered Paper. ESMO. 30 September 2012. 19. Bruno R. Bastos, J. Diamond, R. Hansen, D. Gustafson, J. Arnott, M. Bray, C. Sidor, W. Messersmith, G. Shapiro. An open-label, dose escalation, safety, and pharmacokinetic study of ENMD-2076 administered orally to patients with advanced cancer. Poster Discussion Session, Developmental Therapeutics: Molecular Therapeutics. ASCO 2010. Orlando, FL. 20. Sharma S, Tibes R, Bastos B et al. CBP501, a novel cell cycle dysregulator, in combination with cisplatin (CDDP) and pemetrexed (PM) – results of two phase I/II studies. 2009 AACR-NCI-EORTC Molecular Targets and Cancer Therapeutics Conference. Boston, MA. November 2009. 21. Elgart G, Tzu J, Bastos B. Extramedullary relapse of leukemia cutis limited to the skin. American Society of Dermato-Pathology - 45th Annual Meeting. San Francisco, CA. October 2008. 22. Stefanovic A, Bastos B, Ernst S. Gastric Signet-Ring-Cell Carcinoma Presenting with Leptomeningeal Carcinomatosis - A Case Report. University of Miami Sylvester Comprehensive Cancer Center, 7th Annual Zubrod Lecture and Research Poster Competition, Miami, FL, May 2006. 23. Bastos B, Ramos JC, Cabral L, Harrington WJ. Complete Remission of Oral Plasmablastic Lymphoma with Antiviral Therapy. University of Miami Sylvester Comprehensive Cancer Center, 4th Annual Zubrod Lecture and Research Poster Competition, Miami, FL, May 2003. 24. Coutinho A, Bastos B. Lacrimal Gland Metastasis as the Primary Manifestation of Breast Cancer - A Case Report. Annual Meeting of the Brazilian Society of Clinical Oncology, Florianopolis, SC, Brazil, November 2001. C. Publications 1. Odia Y, Cavalcante L, Safran H, Powell SF, Munster PN, Ma WW, Carneiro BA, Bastos BR, Mikrut S, Mikrut W, Giles FJ, Sahebjam S.Malignant glioma subset from actuate 1801: Phase I/II study of 9-ING-41, GSK-3β inhibitor, monotherapy or combined with chemotherapy for refractory malignancies. Neurooncol Adv. 2022 Feb 7;4(1):vdac012. doi: 10.1093/noajnl/vdac012. eCollection 2022 Jan-Dec.PMID: 35402914. 2. Flaig T, Tangen C, Daneshmand S, Alva A, Lerner S, Lucia MS, McConkey D, Theodorescu D, Goldkorn A, Milowsky M, Bangs R, MacVica G, Bastos BR, et al. A randomized phase II study of coexpression extrapolation (COXEN) with neoadjuvant chemotherapy for bladder cancer (SWOG S1314; NCT02177695). Clin Cancer Res. 2021 Feb 10. 3. Bao R, Surriga O, Olson D, Allred J, Strand C, Zha Y, Call T, Labadie B, Bastos BR et al. Transcriptional analysis of metastatic uveal melanoma survival nominates NRP1 as a therapeutic target. Melanoma Res. 2021 Feb; 3. 4. Sadler D, Chaulagain C, Alvarado B, Cubeddu R, Stone E, Sauel T, Bastos B et al. Practical and cost-effective model to build and sustain a cardio-oncology program. Cardiooncology. 2020 Jul 16. 5. Luke JJ, Olson DJ, Allred JB, Strand CA, Bao R, Zha Y, Carll T, Labadie BW, Bastos BR et al. Randomized phase II trial and tumor mutation spectrum analysis from cabozantinib versus chemotherapy in metastatic uveal melanoma (alliance A091201). Clin Cancer Res. 2020 Feb 15. 6. Gerber DE, Socinski MA, Neal JW, Wakelee HA, Shirai K, Sequist LV, Rosovsky RP, Lilenbaun RC, Bastos BR et al. Randomized phase 2 study of tivantinib plus erlotinib versus single-agent chemotherapy in previously treated KRAS mutant non-small cell lung cancer. Lung Cancer. 2018. Mar. 7. Schroeder JR, Gleason JB, Bastos B, et al. Where is the Air? J Clinic Diagn Res. 2017 Feb. 8. Bastos BR, Lilenbaum RC. Combining EGF receptor inhibitors with chemotherapy or chemoradiotherapy in patients with non-small-cell lung cancer. Therapy. January 2011. 9. Pinto D, et al, Bastos B. Reversible posterior leukoencephalopathy syndrome secondary to Bevacizumab: a case report. J Hematol Oncol Pharm. 2011; 1(2):10-14. 10. Diamond JR, Bastos BR et al. Phase I Safety, Pharmacokinetic and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor, in Patients with Advanced Solid Tumors. Clin Cancer Res February 15, 2011. 11. Shapiro GI, Tibes R, Gordon MS, Wong BY, Eder JP, Borad MJ, Mendelson DS, Vogelzang NJ, Bastos BR et al. Phase I Studies of CBP501, a G2 Checkpoint Abrogator, as Monotherapy and in Combination with Cisplatin in Patients with Advanced Solid Tumors. Clin Cancer Res. 2011 Jan 10. 12. Bastos BR et al. Efficacy and Toxicity of Chemoradiotherapy with Carboplatin and Irinotecan Followed by Consolidation Docetaxel for Unresectable Stage III Non-Small Cell Lung Cancer. J Thoracic Oncol. 2010 Apr.